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目的探讨新生儿呼吸窘迫综合征(NRDS)患儿血清甲状腺激素水平变化及其临床意义。方法采用放射免疫法检测NRDS患儿治疗前后血清甲状腺激素水平变化,并与同期出生的健康对照组进行比较。结果 NRDS组治疗前TT3、FT3均明显低于健康对照组(P<0.01),治疗后与治疗前比较,TT3、FT3水平明显增高(P<0.01),两组TSH、TT4、FT4无明显改变(P>0.05)。结论 NRDS患儿伴有TT3、FT3降低,随着病情的好转,甲状腺功能可恢复正常。
Objective To investigate the changes of serum thyroid hormone in children with neonatal respiratory distress syndrome (NRDS) and its clinical significance. Methods The levels of serum thyroid hormone in children with NRDS before and after treatment were measured by radioimmunoassay and compared with those of healthy controls born in the same period. Results The levels of TT3 and FT3 in NRDS group were significantly lower than those in healthy control group before treatment (P <0.01), and the levels of TT3 and FT3 in NRDS group were significantly higher than those before treatment (P <0.01) (P> 0.05). Conclusion NRDS children with TT3, FT3 decreased, with the condition improved, thyroid function can return to normal.