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目前,已公认采用手术和放疗联合治疗口咽癌效果较好(多数报道其治愈率已达50～60%),但对在术前还是术后进行放疗尚有争议,赞成手术前放疗的依据为:(1)由于肿瘤的血运未被手术破坏,肿瘤供氧情况良好,故对放疗更为敏感;(2)放疗使淋巴通路纤维化乃可对肿瘤进行更多的手术操作并可防止肿瘤的扩散和转移:(3)可使肿瘤皱缩,使一些原来不能切除的肿瘤有了切除的可能。反对术前、支持术后放疗的依据有:(1)术前放疗的术后并发症发生率较高;(2)如有并发症发生则多较严重;(3)在放疗野内的手术操作比较困难;(4)确定肿瘤边界困难,因而可能切除不彻底。作者们在1970～1978年间观察了58例口咽部表皮样癌,平均年龄58岁,男、女之比为5∶1
At present, it has been recognized that surgery and radiotherapy combined to treat oropharyngeal cancer is effective (most reported that the cure rate has reached 50 to 60%), but it is controversial whether radiotherapy is performed before or after surgery, and it is in favor of preoperative radiotherapy. For: (1) Because the tumor’s blood supply is not destroyed by surgery, the tumor has good oxygen supply, so it is more sensitive to radiotherapy; (2) Radiotherapy can make the lymphatic pathway fibrosis can carry out more surgical operations on the tumor and can prevent Diffusion and metastasis of tumors: (3) The tumors can shrink, making it possible to remove some of the tumors that could not be removed. The basis for opposing preoperative and postoperative radiotherapy is: (1) Preoperative radiotherapy has a high incidence of postoperative complications; (2) More serious complications occur; (3) Surgical procedures in the radiotherapy field It is more difficult; (4) It is difficult to determine the boundary of the tumor and it may not be completely removed. The authors observed 58 cases of oropharyngeal epidermoid carcinoma from 1970 to 1978, with an average age of 58 years and a male to female ratio of 5:1.