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目的探讨剖宫产同时挖除子宫肌瘤术中应用益母草注射液预防产后出血的作用。方法回顾性分析枣庄市妇幼保健院于2011年1月至2013年12月因各种原因行剖宫产同时挖除子宫肌瘤的产妇为研究对象。其中对照组(缩宫素组)40例,于胎儿娩出后子宫肌壁注射缩宫素10 U,同时静脉滴注缩宫素10 U,于子宫肌瘤四周及基底部注射缩宫素10U,术后2 h开始缩宫素臀部肌内注射10 U/12 h,共4次;研究组(益母草+缩宫素组)43例,于胎儿娩出后子宫肌壁注射益母草注射液40 mg,术中缩宫素用法同对照组,术后2 h开始益母草注射液臀部肌内注射20 mg/12 h,共4次,观察产时出血量、产后24 h的阴道出血量、产后出血发生率、产前及产后血红蛋白的差值。结果产时出血量、产后24 h的阴道出血量、产前及产后血红蛋白的差值研究组均少于对照组,产后出血发生率研究组较对照组明显降低,差异均有统计学意义(P<0.05)。结论剖宫产同时挖除子宫肌瘤术中应用益母草注射液及缩宫素,可有效预防产后出血的发生。
Objective To investigate the effect of using Motherwort extract in preventing postpartum hemorrhage during cesarean section while removing uterine fibroids. Methods A retrospective analysis of maternal and child health centers in Zaozhuang City from January 2011 to December 2013 for all causes of cesarean section while removing uterine fibroids for the study. In the control group (oxytocin group) 40 cases, uterine muscle wall injection of oxytocin 10 U after injection of the fetus, while intravenous infusion of oxytocin 10 U, uterine fibroids in the surrounding and basal injection of oxytocin 10U, The oxytocin and hips were injected intramuscularly 10 h / 12 h after operation at 2 h after operation. In the study group (motherwort + oxytocin group), 43 cases were injected with 40 mg of Leonurus injection on the uterine muscle wall after the fetus was delivered In the use of oxytocin with the control group, 2 hours after operation Leonurus grass injection intramuscular injection of 20 mg / 12 h, a total of 4 times to observe the amount of bleeding during delivery, vaginal bleeding 24 hours postpartum, the incidence of postpartum hemorrhage, Differences in prenatal and postpartum hemoglobin. Results The amount of bleeding during labor, the amount of vaginal bleeding 24 hours after delivery, the difference between prenatal and postpartum hemoglobin in the study group were less than those in the control group, and the incidence of postpartum hemorrhage was significantly lower in the study group than in the control group (P <0.05). Conclusion Cesarean section while removing uterine fibroids application of Leonurus injection and oxytocin, can effectively prevent the occurrence of postpartum hemorrhage.