近日,来自哈利珀金斯医学研究所的一组研究人员通过研究揭示了1型糖尿病如何干扰机体免疫系统的功能,同时研究者还阐明了个体患1型糖尿病的新型分子机制。相关研究刊登于国际杂志Journal of Immunology上。研究者Grant Morahan教授表示,并不像很多其它的遗传性疾病,引发1型糖尿病的基因往往会通过调节其它基因的表达水平来促使疾病发生,而并不是通过改变蛋白来实现上述过程。在一些遗传性疾病中,比如囊性纤维化疾病,该疾病仅有单一基因突变产生错误的蛋白而引发,诸如 Recently, a group of researchers from the Harper-Perkins Institute of Medicine revealed through research that how type 1 diabetes interferes with the body’s immune system and researchers have elucidated new molecular mechanisms in individuals with type 1 diabetes. Related research is published in the Journal of Immunology. Researchers Professor Grant Morahan said that unlike many other genetic diseases, genes that cause type 1 diabetes often drive the disease by regulating the expression of other genes rather than by altering the protein. In some hereditary diseases, such as cystic fibrosis, the disease is triggered only by a single gene mutation that produces the wrong protein, such as