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目的探讨登革热病的临床特征。方法对108例登革热患者临床资料进行回顾性分析。结果108例患者主要临床表现发热(100%)、畏寒(62.0%)、头痛(76.8%)、肌痛(81.5%)、皮疹/出血点(69.4%),DF-IgM抗体阳性占100%,核酸检测显示感染病毒类型是DEN-Ⅰ型,白细胞和血小板减少分别占85.2%和82.4%,丙氨酸转氨酶(ALT)升高占42.6%,天门冬氨酸转氨酶(AST)升高占79.6%,乳酸脱氢酶(LDH)升高占80.6%,肌酸磷酸激酶(CK)升高占43.5%,β-羟丁酸(β-HBD)升高占69.4%。结论本次珠海市2007年登革热为DEN-I流行,患者临床症状较轻,部分患者伴有心肌损伤,经积极治疗临床恢复较好。
Objective To investigate the clinical features of dengue fever. Methods The clinical data of 108 dengue fever patients were retrospectively analyzed. Results The main clinical manifestations were fever (100%), chills (62.0%), headache (76.8%), myalgia (81.5%), skin rashes / hemorrhage (69.4%) and DF- , The type of virus was detected by nucleic acid detection was DEN-Ⅰ type, white blood cells and thrombocytopenia accounted for 85.2% and 82.4%, alanine aminotransferase (ALT) increased 42.6%, aspartate aminotransferase (AST) increased 79.6 %, Lactate dehydrogenase (LDH) increased 80.6%, creatine phosphokinase (CK) increased 43.5%, β-hydroxybutyrate (β-HBD) increased 69.4%. Conclusion The dengue fever in Zhuhai Municipality was endemic to DEN-I in 2007, with mild clinical symptoms. Some patients were accompanied by myocardial injury, and the active recovery from clinical treatment was better.