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目的:提高对原发性小肠肿瘤的认识及诊治水平。方法:回顾性分析2000年1月至2010年6月收治的88例原发性小肠肿瘤患者的临床资料。结果:88例患者中,良性肿瘤占22.7%(20/88),恶性肿瘤占77.3%(68/88)。良性肿瘤以平滑肌瘤多见,占60.0%(12/20);恶性肿瘤主要为腺癌,占45.6%(31/68)。88例患者主要临床表现依次为腹痛及腹部不适、消化道出血、体重减轻及消瘦、贫血、腹部包块等。本组术前误诊率为62.5%(55/88),全组均行手术治疗,无手术死亡病例。恶性肿瘤1、3、5年生存率分别为74%(37/50)、46.0%(23/50)、24.0%(12/50)。结论:小肠肿瘤临床表现不典型,早期诊断困难,误诊率高,一经诊断,手术治疗是最佳选择。
Objective: To improve awareness of primary small intestinal tumors and diagnosis and treatment. Methods: The clinical data of 88 patients with primary intestinal tumor admitted from January 2000 to June 2010 were retrospectively analyzed. Results: Of 88 patients, benign tumors accounted for 22.7% (20/88), malignant tumors accounted for 77.3% (68/88). Malignant tumors were more common in leiomyomas, accounting for 60.0% (12/20). Malignant tumors were mainly adenocarcinoma, accounting for 45.6% (31/68). The main clinical manifestations of 88 patients were abdominal pain and abdominal discomfort, gastrointestinal bleeding, weight loss and weight loss, anemia, abdominal mass and so on. The preoperative misdiagnosis rate was 62.5% (55/88). All patients underwent surgical treatment without any surgical death. The 1, 3, 5 year survival rates of malignant tumors were 74% (37/50), 46.0% (23/50) and 24.0% (12/50), respectively. Conclusion: The clinical manifestations of small bowel tumors are not typical, early diagnosis is difficult and the rate of misdiagnosis is high. Once diagnosed, surgical treatment is the best choice.