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Paradise等(1978)随访了有频繁咽喉痛发作史的65例儿童,第一年观察结果,发现咽喉痛照样频繁发作而符合切除术条件者只是少数(11例,17％)。其余54例,43例(80％)一年内没有发作,或发作1、2次,10例各发作3次;1例发作4次。但34次发作中有16次未达到规定的临床表现标准,11例中发作的分布无1例符合切除术条件。89次发作中57次(64％)轻度,23次(26％)中度,9次(10％)重度。83次发作中甲型β-溶血性链球菌培养阳性者30次(36％)。 54例中第2年随访22例:其中1例因复发性感染,2例因阻塞症状而符合切除术条件;7例无发作;7例各发作1次;5例各发作2次。17次发作中轻度或重度共13次。
Paradise et al. (1978) followed 65 children with a history of frequent episodes of sore throat. In the first year of observation, they found frequent episodes of sore throat and only a minority of those eligible for resection (11, 17%). The remaining 54 cases, 43 cases (80%) did not attack within a year, or attack 1, 2 times, 10 cases of each attack 3 times; 1 case attack 4 times. However, 16 of the 34 attacks did not meet the prescribed clinical performance criteria, and none of the 11 patients were eligible for resection. 57 episodes (64%) mild, 23 (26%) moderate, and 9 (10%) severe in 89 seizures. Thirty (36%) were positive for beta-hemolytic streptococci in 83 seizures. Of the 54 cases, 22 were followed up for the second year of follow-up: one of them was due to recurrent infection and two had obstruction due to obstruction; seven had no seizures; seven had seizures each; and five had seizures twice. 17 episodes mild or severe total of 13 times.