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目的分析冠状动脉粥样硬化性心脏病女性患者与血清中尿酸水平的关系。方法 113例疑诊冠状动脉粥样硬化性心脏病(冠心病)女性患者,根据其冠状动脉造影结果分为观察组(冠心病组)57例和对照组(非冠心病组)56例,检测患者血清尿酸水平并对其及两组一般资料做对比分析,然后做多元回归分析。结果观察组肌酐、总胆固醇(TC)、甘油三酯(TG)、血糖、体质量指数(BMI)、舒张压(DBP)与对照组比较,差异无统计学意义(P>0.05);观察组尿酸、年龄、收缩压(SBP)明显高于对照组,差异有统计学意义(P<0.05);进一步进行Logistic回归分析表明,尿酸、年龄、SBP是冠心病的危险因素。结论患者尿酸水平的增高能够成为冠心病女性患者的危险因素,临床治疗过程中,要注意检测女性血清尿酸水平,关键时给予相应的干预。
Objective To analyze the relationship between serum uric acid and female patients with coronary atherosclerotic heart disease. Methods A total of 113 women with coronary heart disease (CHD) were divided into observation group (coronary heart disease group) 57 cases and control group (non-coronary heart disease group) 56 cases according to their coronary angiography results. Serum uric acid levels in patients with two sets of general information and do comparative analysis, and then do multiple regression analysis. Results There was no significant difference in creatinine, total cholesterol (TC), triglyceride (TG), blood glucose, body mass index (BMI) and diastolic blood pressure (DBP) between the observation group and the control group Uric acid, age, systolic blood pressure (SBP) were significantly higher than the control group, the difference was statistically significant (P <0.05); further Logistic regression analysis showed that uric acid, age, SBP are risk factors for coronary heart disease. Conclusions Patients with elevated uric acid levels may become risk factors for women with coronary heart disease. During the course of clinical treatment, serum uric acid levels should be monitored in women and corresponding interventions should be given at the critical point.