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通过许多体内外实验观察新药CI－ooe——血管紧张素对（Aug巨）a飞型受体措抗剂的作用，并与其它ATI受体持抗剂治沙坦（losartan），SKgyl08566和L－158809进行比较。发现CI－996能特异性取代大鼠肝细胞膜上结合的＊呵」Aug正（ICs。一0．8士0·lggol·L－‘；洛沙MIC。。一12
The effect of a novel drug, CI-ooe-angiotensin, on the (Ach) a-type receptor antagonist was observed by many in vitro and in vivo experiments and compared with other ATI receptor antagonists losartan, SKgyl08566 and L -158809 for comparison. CI-996 was found to specifically replace the rat liver cell membrane binding * Oh positive (ICs. A 0.8 ± 0. lggol · L- ’; Losa MIC .. a 12