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目的研究对比腹会阴联合直肠癌根治术(Miles术)与保肛术应用于直肠癌患者治疗中的效果。方法 78例直肠癌患者,以随机原则分为对照组与观察组,各39例。对照组实施Miles术,予以观察组保肛术治疗。观察两组患者治疗前后生活质量及随访期间的复发情况。结果治疗前对照组与观察组生活质量量表评分分别为(51.19±4.85)分和(51.87±4.69)分,对比差异无统计学意义(P>0.05);经不同治疗后,观察组生活质量量表评分为(82.37±3.15)分,对照组为(70.92±4.60)分,两组比较,观察组明显优于对照组,差异具有统计学意义(P<0.05)。在为期6个月的随访中,对照组中有5例患者复发,复发率为12.82%;观察组中有2例患者复发,复发率为5.13%。在复发情况方面,两组比较差异无统计学意义(P>0.05)。结论保肛术应用于直肠癌患者的治疗中,效果显著,能够控制疾病发展,且无需进行肠造口操作,患者更易接受,对其生活质量的提高具有一定积极作用。
Objective To study the effect of contralateral perineum combined with rectal cancer (Miles operation) and anal sphincter preservative in the treatment of patients with rectal cancer. Methods 78 patients with rectal cancer were randomly divided into control group and observation group, with 39 cases in each. The control group Miles operation, the observation group to protect anal surgery. The quality of life before and after treatment and the relapse during follow-up were observed in both groups. Results Before treatment, the quality of life scales of the control group and the observation group were (51.19 ± 4.85) and (51.87 ± 4.69) points respectively, with no significant difference (P> 0.05). After different treatment, the quality of life The scale score was (82.37 ± 3.15) points in the control group and (70.92 ± 4.60) points in the control group. The observation group was significantly better than the control group, the difference was statistically significant (P <0.05). During the 6-month follow-up, 5 patients in the control group relapsed with a recurrence rate of 12.82%. Two patients in the observation group relapsed with a recurrence rate of 5.13%. In recurrence, there was no significant difference between the two groups (P> 0.05). CONCLUSIONS: Anal sphincter is effective in the treatment of patients with rectal cancer. It can control the development of the disease and does not require colostomy. Patients are more receptive and have a positive effect on their quality of life.