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作者分析了105例中枢神经系统(CNS)淋巴瘤患者的临床特征、组织学和预后因素,介绍了CNS淋巴瘤的诊断、治疗和CNS预防性治疗的作用。 105例病人中94例是确诊的,11例是可疑脑膜或实质性CNS淋巴瘤患者;前者脑脊液(CNF)细胞学,尸检或CNS组织活检证实有恶性淋巴瘤,后者符合以下标准:1.已有颅外淋巴瘤;2.伴有不明原因的CNS症状或体征;3.“可疑”CSF细胞学结果或放射核素或计算机体层脑扫描(CT)或脑血管造影证实CNS结
The authors analyzed clinical features, histology, and prognostic factors in 105 patients with central nervous system (CNS) lymphomas, and introduced the role of CNS lymphoma diagnosis, treatment, and prophylactic CNS therapy. Ninety-four out of 105 patients were confirmed, and 11 were suspicious meninges or patients with CNS lymphoma. The former had cerebrospinal fluid (CNF) cytology, autopsy or CNS biopsy confirmed malignant lymphoma, and the latter met the following criteria: 1. There are extracranial lymphomas; 2. Symptoms or signs of CNS with unexplained causes; 3. Suspicious CSF cytology results or radionuclide or computed tomographic brain scan (CT) or cerebral angiography to confirm CNS