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应用单克隆抗体作为肿瘤细胞的诊断和治疗手段已有大量报道。我们从人胃低分化粘液腺癌细胞MGC—80—3中分离了一种癌细胞蛋白,以这种蛋白为抗原免疫产蛋白母鸡,从免疫过的母鸡产蛋之卵黄中分离出一种IgY抗体。这种IgY抗体对人低分化粘液腺癌细胞具有选择性识别作用。IgY
The use of monoclonal antibodies as a tumor cell diagnosis and treatment has been a lot of reports. We isolated a cancer cell protein from human gastric poorly differentiated mucinous adenocarcinoma cell line MGC-80-3 to immunoprecipitate the hen with this protein as an antigen, isolated from the egg yolk of the immunized hen IgY antibody. This IgY antibody has a selective recognition of human poorly differentiated mucinous adenocarcinoma cells. IgY