Influence of the Calmodulin Antagonist EBB on Cyclin B1 and Cdc2-p34 in Human Drug-resistant Breast

来源 :中国肿瘤临床：英文版 | 被引量 : 0次 | 上传用户：jacykeaichenai

【摘要】

：

OBJECTIVE To investigate the influence of O-(4-ethoxyl-butyl)- berbamine(EBB)on the expression of cyclin B1 and cdc2-p34 in the human drug-resistant breast canc

【作者】

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Xu Shi Yanhong Cheng Linglin Z

【机构】

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NationalKeyLaboratoryofExperimentalHematology

【出处】

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中国肿瘤临床：英文版

【发表日期】

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2008年2期

【关键词】

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乳腺癌细胞周期蛋白细胞凋亡治疗方法 EBB cell cycle cyclinB1 cdc2-p34 apoptosis Ca^2＋.

【基金项目】

：

This work was supported by grants from the National Nature Science Foundation of China （No. 30572203, 30570772） and the Key Fund of Science of TianJin Municipal Government （No. 07JCZDJC04900）.

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OBJECTIVE To investigate the influence of O-(4-ethoxyl-butyl)- berbamine(EBB)on the expression of cyclin B1 and cdc2-p34 in the human drug-resistant breast cancer MCF-7/ADR cell line. METHODS The MTT assay was used to assess the cytotoxicity of EBB.Differ

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Influence of the Calmodulin Antagonist EBB on Cyclin B1 and Cdc2-p34 in Human Drug-resistant Breast

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