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目的总结膀胱小细胞癌的诊断及治疗。方法 2009年8月1例行根治性膀胱切除、回肠代膀胱术患者经病理学、免疫组织化学检查确诊为膀胱小细胞癌。患者接受EP治疗方案治疗。结果治疗4周期后,复查CT未见转移,无Ⅲ～Ⅳ级毒副反应。结论膀胱小细胞癌需依靠病理学及免疫组织化学检查确诊,治疗目前参考小细胞肺癌治疗方案,以化学疗法为主,复习文献得出有无手术切除并不影响膀胱小细胞癌患者的预后,靶向药物的治疗尚需进一步研究。
Objective To summarize the diagnosis and treatment of bladder small cell carcinoma. Methods A radical cystectomy was performed in August 2009. The ileal neobladder was diagnosed as bladder small cell carcinoma by pathology and immunohistochemistry. Patients undergoing EP treatment regimen. Results After 4 cycles of treatment, there was no metastasis after CT examination, and no grade Ⅲ ~ Ⅳ toxicities were observed. Conclusions Small cell carcinoma of the bladder needs to be diagnosed by pathology and immunohistochemical examination. At present, the treatment of small cell lung cancer is referred to the chemotherapy regimen. Reviewing the literature, it is concluded that the surgical resection does not affect the prognosis of patients with small cell carcinoma of the bladder. Targeted drug therapy needs further study.