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目的探讨异位垂体腺瘤的组织学特点、诊断要点及鉴别方法。方法对2例异位垂体腺瘤进行组织学观察和免疫组化标记,并结合相关的文献复习。结果异位垂体腺瘤免疫组化:瘤细胞CK(+)、Syn(+)、NSE(+)、CgA(+)、TSH(+)、GH弱(+)、ACTH(-)、LH(-)、FSH(-)、Hpl(-)。结论异位垂体腺瘤是一种少见的垂体肿瘤,通过组织学、免疫组化、影像学及实验室检查可做出准确诊断并及时手术治疗,提高治愈率。
Objective To investigate the histological features, diagnosis points and identification methods of ectopic pituitary adenomas. Methods Two cases of ectopic pituitary adenomas were histologically observed and immunohistochemically labeled, and the related literatures were reviewed. Results Immunohistochemistry of ectopic pituitary adenomas showed that CK (+), Syn (+), NSE (+), CgA (+), TSH (+), GHwere (+), ACTH (-), LH -), FSH (-), Hpl (-). Conclusion Ectopic pituitary adenoma is a rare pituitary tumor. Through histology, immunohistochemistry, imaging and laboratory tests can make accurate diagnosis and timely surgical treatment to improve the cure rate.