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目的探讨口服降糖药物在治疗酮症倾向糖尿病问题上的临床效果,为今后的临床实践提供医学指导。方法选取我院2011年3月～2013年6月收治酮症倾向糖尿病患者60例,按照其入院顺序进行编号、抽取,奇数为对照组,偶数为观察组,各30例。观察组口服降糖药物治疗,对部分病情无改善者采用胰岛素治疗;对照组则采用胰岛素治疗。然后收集所有患者的临床资料,对其结果进行回顾性分析。结果观察组中病情明显改善者26例(86.7%),在C肽水平、FPG以及HbA1c方面,26例患者与治疗前相比差异具有显著性意义(P<0.05);其余4例病情未改善者的C肽水平低于对照组(P<0.05)。结论口服降糖药物可明显改善酮症倾向糖尿病患者的病情,值得推广。
Objective To investigate the clinical effect of oral hypoglycemic agents on the treatment of ketosis prone diabetes and provide medical guidance for future clinical practice. Methods Sixty patients with ketosis-prone diabetes who were admitted to our hospital from March 2011 to June 2013 were selected and numbered according to their order of admission. The patients in the control group were given odd numbers, while the others in the observation group were 30 in each. The observation group oral hypoglycemic drug treatment, some of the condition did not improve insulin treatment; control group was treated with insulin. All patients were then collected for clinical data and their results were retrospectively analyzed. Results 26 cases (86.7%) had significant improvement in the observation group. There were significant differences in the levels of C-peptide, FPG and HbA1c between the 26 patients and before treatment (P <0.05); the other 4 patients did not improve The level of C-peptide was lower in the control group (P <0.05). Conclusion Oral hypoglycemic drugs can significantly improve the symptoms of ketosis prone diabetic patients, it is worth promoting.