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本文研究联合应用有抗病毒作用的无环鸟苷(acyclovir,ACV)和有免疫调节作用的胸腺生成素(thymopentin,TP5),治疗高度复发性或严重性的疱疹感染。 选择22例复发性生殖器疱疹(GH)或口面单纯疱疹(OFHS)发展为多形红斑(EM)的病人用ACV治疗3个月然后皮下注射TP5,最后比较治疗前后疱疹的复发率。22例患者至少有5年发作史,其中9例OFHS患者,平均复发率6.11次/年,13例GH患者,平均复发次数8.67次/年,转为EM的复发率为6.37次/年。
This article studies the combined use of antiviral acyclovir (ACV) and immunomodulatory thymopentin (TP5) to treat highly recurrent or severe herpes infections. 22 patients with recurrent genital herpes (GH) or OFHS who developed erythema multiforme (EM) were treated with ACV for 3 months and then injected with TP5 subcutaneously. Finally, the recurrence rate of herpes before and after treatment was compared. Of the 22 patients who had at least 5 years of history of attack, 9 of them had an average recurrence rate of 6.11 beats per year, 13 of GH patients had an average of 8.67 beats per year and 6.37 beats per year for patients with OFHS.