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目的了解北京市顺义区18~24月龄儿童接种麻风腮疫苗后,流腮成分疫苗的基础免疫效果和麻疹、风疹成分疫苗的复种效果。方法采集36名北京市顺义区18~24月龄儿童麻风腮疫苗免疫前和免疫后1个月双份血标本,ELISA法定量检测麻疹、风疹、流腮Ig G抗体。结果 36名监测对象麻风腮疫苗中流腮成分免疫前抗体阳性率为2.78%,免疫后抗体阳转率为97.22%。麻疹、风疹成分复种前抗体阳性率均为97.22%,抗体活性量值分别为(1 192.31±426.36)和(186.30±92.02)IU/ml;复种后麻疹、风疹抗体阳性率均为100%,抗体活性量值分别为(1 416.83±224.64)和(283.52±90.83)IU/ml,均明显升高(P<0.05)。结论麻风腮疫苗的复种具有重要意义,流腮基础免疫成功率为100%,麻疹、风疹成分复种能提高麻疹、风疹的抗体水平,有效保护儿童免受麻疹、风疹、流行性腮腺炎的侵袭。
Objective To understand the basic immunization effect of mumps vaccine and measles and rubella vaccination after immunization of children with MMR from 18 to 24 months old in Shunyi District of Beijing. Methods Twelve blood samples were collected from 36 children aged 18-24 months old in Shunyi District of Beijing before immunization and one month after immunization. Ig G antibody of measles, rubella and mumps were quantitatively detected by ELISA. Results The positive rate of antibody against grifal cheek in 36 subjects was 2.78% before immunization, and the positive rate of antibody immunization after immunization was 97.22%. The positive rates of measles and rubella were 97.22% and the antibody activity were (1 192.31 ± 426.36) and (186.30 ± 92.02) IU / ml, respectively. The positive rates of measles and rubella were 100% The activity values were (1 416.83 ± 224.64) and (283.52 ± 90.83) IU / ml respectively, both significantly increased (P <0.05). Conclusion The multiple vaccination of mumps vaccine is of great significance. The success rate of basic immunization of mumps is 100%. The multiplication of measles and rubella can increase the antibody level of measles and rubella and effectively protect the children from measles, rubella and mumps.