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目的:探讨胎膜早破与生殖道感染及不良妊娠结局的关系。方法:选择胎膜早破产妇292例(早破组)及同期住院无胎膜早破分娩产妇200例(对照组),对两组进行生殖道病原微生物检测,同时观察分析两组不良妊娠结局。结果:早破组细菌性阴道病、衣原体感染及念珠菌感染阳性率与对照组各项均存在显著性差异(P<0.05);早破组围产儿的早产率与对照组存在高度显著性差异(P<0.01),同时早破组围产儿的感染率与对照组也存在显著性差异(P<0.05)。结论:胎膜早破与生殖道感染密切相关,应重视孕期生殖道病原微生物检测,对生殖道感染者进行及时有效的治疗,预防和减少不良妊娠结局的发生。
Objective: To investigate the relationship between premature rupture of membranes and reproductive tract infections and adverse pregnancy outcomes. Methods: 292 cases of premature rupture of membranes (premature rupture) and 200 cases of maternal premature rupture of membranes (control group) during the same period were enrolled in this study. Pathogenic microorganisms were detected in both groups, meanwhile, adverse pregnancy outcomes . Results: The rates of bacterial vaginosis, chlamydial infection and candidiasis in premature rupture group were significantly different from those in control group (P <0.05). The rate of preterm birth in premature rupture group was significantly higher than that in control group (P <0.01). At the same time, the rate of perinatal infection in premature rupture group was also significantly different from that in control group (P <0.05). Conclusion: Premature rupture of membranes is closely related to genital tract infection. It should pay attention to the detection of pathogenic microorganisms in the reproductive tract during pregnancy, and treat the genital tract patients timely and effectively to prevent and reduce the incidence of adverse pregnancy outcomes.