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某种体征出现于距离罹患脏器很远的部位,尽管发生机制尚不明确,但在临床上却受到了重视。如肺疾患与杵状指,肝疾患与蜘蛛痣等都是很好的例子。就冠状动脉疾患而言也有报告此类体征的。即1973年Frank指出于耳垂上可见到皱褶,第二年Lichstein等查明耳垂皱褶出现在急性心肌梗塞患者很多。认为此体征可提示冠状动脉疾患的存在。此后,对于临床上诊断冠状动脉疾患的患者、受过冠状动脉造影检查的患者,经剖检,查明了此体征与冠状动脉疾患相互关联。
Some signs appear in far away from the organs of the disease, although the mechanism is not clear, but it has been clinically valued. Such as lung disease and clubbing, liver disease and spider nevus are all good examples. Such signs are also reported in the context of coronary artery disease. In 1973 Frank pointed out that the earlobes can be seen folds, the next year Lichstein found earlobes wrinkles in patients with acute myocardial infarction a lot. Think this sign may suggest the presence of coronary artery disease. Since then, in patients with clinically diagnosed coronary artery disease, patients undergoing coronary angiography have undergone an autopsy to ascertain that this sign correlates with coronary artery disease.