分子生物学方法在腮腺炎病毒感染疾病诊断方面获得广泛应用。分子流行病学调查证明病毒流行株基因漂变。病毒神经毒力检查及疫苗接种后脑炎发病机理探讨表明病毒的遗传基因型是致病的决定性因素。现有的多种疫苗与腮腺炎疫苗同时接种均不影响其免疫效果。新一代疫苗开发及全球范围消灭流行性腮腺炎也取得了明显进展 Molecular biological methods are widely used in the diagnosis of mumps virus infection. Molecular epidemiological investigation proved that the virus epidemic strains gene drift. Examination of the virus neurovirulence and the pathogenesis of post-vaccination encephalitis show that the genetic type of the virus is the determinant of the disease. The existing vaccines and mumps vaccination at the same time does not affect the immune effect. Significant progress has also been made in the development of a new generation of vaccines and in the global elimination of mumps