吻合口瘘是食管、贲门癌切除术后最严重的并发症之一。本院自1970年12月至1990年5月共行食管、贲门癌切除术718例,发生胸内吻合口瘘11例(1.5％)。1985年以前5例采用一般保守治疗,在院死亡2例,自动出院3例。近年来采用抗菌素生理盐水胸腔灌洗加持续负压吸引引流法治疗9例(其中3例为收治外院病例),全部治愈出院。现将灌洗的方法和体会介绍如下:胸内吻合口瘘一经确诊,即在引流最通畅的位置放置粗胸管,以利充分引流大量食物渣和脓液。对 Anastomotic fistula is one of the most serious complications after resection of esophageal and cardiac cancers. From December 1970 to May 1990, 718 cases of esophageal and cardiac cancer resection were performed in our hospital. 11 cases (1.5%) of intrathoracic anastomotic leakage occurred. Before 1985, 5 cases were treated with general conservative treatment, 2 cases died in the hospital, and 3 cases were discharged automatically. In recent years, 9 cases (including 3 cases of hospitalized patients) were treated with antibiotics saline pleural lavage plus continuous negative pressure suction and drainage. All were cured and discharged. Now the method and experience of lavage are described as follows: Once the anastomosis fistula in the chest has been diagnosed, the thoracic tube is placed in the most fluent position to facilitate drainage of large amounts of food scum and pus. Correct