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目的调查基于淮安市2010年出生人群的围产新生儿流行病学中出生缺陷发生率、主要的出生缺陷分布及出生缺陷新生儿的死亡率。方法采用描述性流行病学调查方法,对2010年淮安市全部出生新生儿信息进行前瞻性收集。结果2010年出生缺陷发生率为6.7‰。主要的出生缺陷依次为唇裂和腭裂,肌肉骨骼系统,循环系统,神经系统,生殖泌尿系统等。有出生缺陷的死胎、死产或生后新生儿死亡率为20.4%。结论淮安出生缺陷发生率低于国外和国内的大部分报道,加大出生缺陷的三级预防和监测工作,才能进一步降低新生儿死亡率。
Objective To investigate the prevalence of birth defects, the distribution of major birth defects and the neonatal mortality rate of birth defects in the perinatal neonates based on the population born in 2010 in Huaian City. Methods A descriptive epidemiological survey method was used to prospectively collect all the newborn infants born in Huai’an in 2010. Results The incidence of birth defects in 2010 was 6.7 ‰. The main birth defects followed by cleft lip and cleft palate, musculoskeletal system, circulatory system, nervous system, genitourinary system and so on. A stillborn child with a birth defect has a 20.4% mortality rate of stillbirth or postnatal newborn. Conclusions The incidence of birth defects in Huai’an is lower than most of the reports from abroad and in China. To increase the tertiary prevention and monitoring of birth defects can further reduce the neonatal mortality rate.