论文部分内容阅读
目的 研究SARS患者治疗期间发生药品不良反应的相关危险因素。方法 回顾性分析小汤山医院临床确诊的6 80例SARS患者的病案、用药纪录及药品不良反应发生情况 ,研究年龄、性别、病情、给药途径和各大类药物对药品不良反应发生的影响。结果 女性患者的ADRs发生率要略高于男性患者 ;老年和重症型患者的ADRs发生率明显高于中青年和普通型患者 ;免疫调节剂、糖皮质激素、抗病毒药和抗菌药四大类药物的ADRs发生率较高 ;各种给药途径对ADRs发生率无明显影响。结论 年龄、病情和性别等为药品不良反应发生的相关危险因素。
Objective To study the risk factors associated with adverse drug reactions in patients with SARS during treatment. Methods A retrospective analysis of the clinical diagnosis of Xiaotangshan Hospital of 80 cases of SARS patients with medical records, drug records and adverse drug reactions to study the age, gender, condition, route of administration and various types of drugs on adverse drug reactions occurred. Results The incidence of ADRs in female patients was slightly higher than that in male patients. The incidence of ADRs in elderly and critically ill patients was significantly higher than that in middle-aged and young patients. The immunomodulatory agents, glucocorticoids, antiviral drugs and antibacterial drugs Of the incidence of ADRs higher; various routes of administration had no significant effect on the incidence of ADRs. Conclusions Age, illness and gender are the related risk factors of ADR.