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左室重构是指急性心肌梗死(AMI)后左心室发生结构与功能的改变,并且心肌细胞发生肥大及表型改变[1]。包括早期的梗死区伸展和晚期的整体心室扩张,这些是导致心脏衰竭的重要因素。1 AMI后左室重构的机制1.1血流动力学因素梗死区伸展是AMI早期引起左室重构的主要原因。心肌梗死后,部分心肌缺血坏死,失去收缩功能,左心室室壁收
Left ventricular remodeling is the change of structure and function of left ventricle after acute myocardial infarction (AMI), and cardiomyocyte hypertrophy and phenotypic changes [1]. Including early infarct zone extension and late global ventricular dilatation, which are important contributors to heart failure. 1 AMI mechanism of left ventricular remodeling 1.1 hemodynamic factors infarct stretch is the main cause of AMI early left ventricular remodeling. Myocardial infarction, myocardial ischemia and necrosis, loss of systolic function, left ventricular wall closed