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目的探讨CT灌注检查在乳腺疾病诊断中的应用价值。资料与方法将22例分为乳腺癌组和乳腺炎症组行CT灌注检查,采用GE AW4.1工作站perfusion 3体部肿瘤灌注软件行图像后处理,得出各组灌注参数值并与正常乳腺组织进行对照分析。结果乳腺癌组、乳腺炎症组表面通透性(PS)、血容量(BV)、血流量(BF)平均值均高于正常乳腺组织,其差异具有统计学意义(P<0.05)。乳腺炎症组PS、BV平均值高于乳腺癌组,两者差异具有统计学意义(P<0.05)。平均通过时间(MTT)值差异均无明显统计学意义(P>0.05)。术后瘢痕区PS、BV、BF平均值低于正常乳腺组织。结论CT灌注检查可以反映乳腺病变的血流灌注及功能学改变,是诊断乳腺病变可行的辅助检查方法。
Objective To investigate the value of CT perfusion in the diagnosis of breast diseases. Materials and Methods Twenty-two cases were divided into breast cancer group and mammary gland inflammation group underwent CT perfusion examination. The images were processed by GE AW4.1 workstation perfusion 3 tumor perfusion software, and the perfusion parameters were obtained and compared with normal breast tissue Control analysis. Results The average values of surface permeability (PS), blood volume (BV) and blood flow (BF) in breast cancer group and breast inflammation group were significantly higher than those in normal breast tissue (P <0.05). The average value of PS and BV in mastitis group was higher than that in breast cancer group, the difference was statistically significant (P <0.05). Mean difference in transit time (MTT) values were not statistically significant (P> 0.05). Postoperative scar area PS, BV, BF average lower than normal breast tissue. Conclusion CT perfusion examination can reflect the changes of blood flow perfusion and functional changes in breast lesions. It is a feasible auxiliary examination for the diagnosis of breast lesions.