产妇28岁,孕30周。无诱因血压升高、视物不清急诊入院。检查:Bp 200/130mm Hg,双下肢Ⅱ度浮肿,胎动>3次/h。尿蛋白34mg/dl(4+),血HGB:97 g/L,ALB:21.4 g/L,BNP:809 pg/ml,临床诊断重度子痫前期,低蛋白血症。胎儿超声:胎儿大小相当于28+1周,脐带绕颈一周,脐带迂曲变细,盘旋似“麻花”样(图1),胎盘侧血流充填较差,流速较缓,S/D明显增高。胎儿心率偏 Maternal 28 years pregnant 30 weeks. No incentive to high blood pressure, depending on the material is not clear emergency hospitalization. Check: Bp 200 / 130mm Hg, Ⅱ lower extremity edema, fetal movement> 3 times / h. Urine protein 34mg / dl (4+), blood HGB: 97g / L, ALB: 21.4g / L, BNP: 809pg / ml, clinical diagnosis of severe preeclampsia, hypoproteinemia. Fetal ultrasound: fetal size equivalent to 28 + 1 week, the umbilical cord around the neck a week, the umbilical cord tortuous thinning, hovering like “twist” like (Figure 1), poor placental blood flow filling, slow flow, S / D Significantly higher. Fetal heart rate bias