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目的分析研究地屈孕酮联合人绒毛膜促性腺激素(HCG)治疗复发性流产患者的临床疗效。方法将复发性流产患者51例随机分为两组,观察组给予地屈孕酮联合HCG治疗,对照组给予黄体酮治疗,观察比较两组治疗效果。结果观察组26例患者中妊娠成功及足月分娩21例(80.77%),流产5例(19.23%);对照组25例患者中妊娠成功及足月分娩11例(44.00%),流产14例(56.00%),两组比较差异有统计学意义(P<0.05)。两组均无严重不良反应发生。结论地屈孕酮联合HCG治疗复发性流产明显能提高患者足月妊娠率,有较可靠的应用价值,值得推广。
Objective To study the clinical efficacy of dydrogesterone combined with human chorionic gonadotropin (HCG) in the treatment of recurrent spontaneous abortion. Methods Fifty-one patients with recurrent spontaneous abortion were randomly divided into two groups. The patients in the observation group were treated with dydrogesterone combined with HCG and the control group with progesterone. The therapeutic effect was observed and compared between the two groups. Results Among 26 patients in observation group, 21 cases (80.77%) had successful pregnancy and term delivery and 5 cases (19.23%) had abortion. In the control group, 11 cases (44.00%) were successful and full term delivery were delivered in pregnancy, and 14 cases (56.00%), the difference between the two groups was statistically significant (P <0.05). No serious adverse reactions occurred in both groups. Conclusion Dydrogesterone combined with HCG in the treatment of recurrent spontaneous abortion significantly improve the full-term pregnancy rate in patients with more reliable application value, which is worth promoting.