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目的 探讨蟾酥素治疗尖锐湿疣的疗效。方法 对我院372例尖锐湿疣在祛除疣体后,基底部按注射药物不同随机分为蟾酥素组、5-Fu组、生物因子组及对照组。各组分别皮内注射相应药物,对照组不注射药物。观察3月以上。结果 尖锐湿疣一次性治愈率分别为76.66%、60.76%、71.96%、50.70%。2月后复发率分别为5.55%、20.53%、15.91%、32.39%。经X2检验,一次性治愈率蟾酥素组与生物因子组、5-Fu组相接近,与对照组相比有显著差异(P<0.05)。复发率蟾酥素组均低于各组,有显著及非常显著差异(P<0.05,P<0.01)。结论 尖锐湿疣在祛除疣体后,基底部注射蟾酥素可以提高一次治愈率及降低复发率。
Objective To investigate the therapeutic effect of cinobufotalin on condyloma acuminatum. Methods 372 cases of condyloma acuminatum in our hospital wiped off warts, the base of the injection of drugs according to different randomly divided into civencin group, 5-Fu group, biological factors and control group. Each group were injected with the corresponding drug intradermally, the control group did not inject the drug. Observed in March or more. Results One-time cure rate of genital warts were 76.66%, 60.76%, 71.96% and 50.70% respectively. The recurrence rates in February were 5.55%, 20.53%, 15.91% and 32.39% respectively. After X2 test, the one-time cure rate of civenin group and biological factor group, 5-Fu group close, compared with the control group were significantly different (P <0.05). The recurrence rate of the group were lower than that of each group, there was a significant and very significant difference (P <0.05, P <0.01). Conclusion Condyloma acuminata warts in the removal of the body, basal injection of cinobufogenin can improve the cure rate and reduce the recurrence rate.