论文部分内容阅读
目的:观察枳术康胃汤联合吗丁啉治疗消化不良的疗效。方法:将本卫生室2012年12月-2014年8月收治的90例消化不良患者随机分为对照组与观察组2组,每组各45例。对照组采取吗丁啉方案,观察组则加用枳术康胃汤方案,比较2组患者的近期疗效,及不良反应率、复发率。结果:总有效率观察组为95.56%,对照组为71.11%,2组比较,差异有统计学意义(P<0.05)。观察组治疗前后中医症状总积分分别为(10.12±2.89)分、(5.23±2.12)分,对照组分别为(10.11±2.91)分、(8.14±1.76)分,2组患者治疗后中医症状总积分比较,差异有统计学意义(P<0.05)。对照组7例出现全身不良反应,腹泻3例,腹痛4例,减量后缓解,不良反应率15.56%;观察组2例患者大便出现稀糊状,4天后缓解,不良反应率4.44%。2组不良反应发生率比较,差异无统计学意义(P>0.05);随访3月,观察组复发1例,占2.33%,对照组复发8例,占25.00%;2组复发率比较,差异有统计学意义(P<0.05)。结论:在消化不良患者的临床治疗中,采用枳术康胃汤联合吗丁啉方案,疗效确切,复发率低,值得推广。
Objective: To observe the effect of Zhizu Kang Wei Decoction combined with domperidone in treating indigestion. Methods: Ninety patients with dyspepsia admitted from December 2012 to August 2014 in our clinic were randomly divided into control group and observation group, with 45 cases in each group. The control group to domperidone program, the observation group was added Zhizu Kang stomach soup program, the two groups of patients with short-term efficacy, and adverse reactions, recurrence rate. Results: The total effective rate was 95.56% in the observation group and 71.11% in the control group. There was significant difference between the two groups (P <0.05). The total scores of TCM symptoms before and after treatment in the observation group were (10.12 ± 2.89) points and (5.23 ± 2.12) points respectively, while those in the control group were (10.11 ± 2.91) and (8.14 ± 1.76) points respectively. Points were compared, the difference was statistically significant (P <0.05). There were 7 cases of systemic adverse reactions in the control group, 3 cases of diarrhea and 4 cases of abdominal pain. The patients were relieved after reduction and the rate of adverse reactions was 15.56%. The stool of 2 cases in the observation group appeared thin paste and remitted 4 days later. The rate of adverse reactions was 4.44%. There was no significant difference in the incidence of adverse reactions between the two groups (P> 0.05). In the follow-up period of March, the observation group recurred in 1 case (2.33%) and in the control group (8.00%), accounting for 25.00% There was statistical significance (P <0.05). Conclusion: In the clinical treatment of patients with dyspepsia, the use of zhizhukang soup combined with domperidone regimen, the exact effect, low recurrence rate, it is worth promoting.