论文部分内容阅读
目的探讨ABO同型血交叉配血不合的影响因素及其处理对策。方法采用微柱凝胶法进行交叉配血,对交叉配血不合的血标本再以凝聚胺法及抗人球蛋白试验进行验证,同时进行不规则抗体筛选及特异性鉴定,结合临床病史资料进行综合分析,找出交叉配血不合的影响因素及适当的处理对策。结果在98例交叉配血不合的血标本中,由不规则抗体引起的有35例(35.7%),冷凝集素引起的有24例(24.5%),自身抗体引起的有18例(18.4%),新生儿溶血病引起的有12例(12.2%),血浆蛋白异常引起的有6例(6.1%),输注药物引起的有3例(3.1%)。98例交叉配血不合中,主侧配血不合68例(69.4%),次侧配血不合18例(18.4%),主次侧均不合12例(12.2%)。结论 ABO同型血交叉配血不合时,首先应找出交叉配血不合的影响因素,按操作规程进行相关试验,结合临床病史资料进行综合分析,以提高交叉配血结果的准确性。
Objective To investigate the influencing factors and treatment strategies of ABO same blood cross mismatch. Methods Cross-matching blood was obtained by micro-column gel method. Blood samples with different cross-matching blood were verified by agglutination test and anti-human globulin test. At the same time, irregular antibody screening and specific identification were carried out, combined with clinical history data Comprehensive analysis to find out the impact of cross-mismatched factors and appropriate treatment measures. Results Of the 98 cases of non-matched blood samples, 35 cases (35.7%) were caused by irregular antibodies, 24 cases (24.5%) were caused by cold agglutinin, 18 cases were caused by autoantibodies (18.4% ), Hemolytic disease in newborns (12.2%), plasma protein abnormalities in 6 (6.1%), and infusions in 3 (3.1%). There were 68 cases (69.4%) with mismatch of blood on the primary side and 18 cases (18.4%) on the secondary side, and 12 cases (12.2%) on the primary side and the secondary side. CONCLUSIONS: When the ABO blood with the same type of blood is not matched with each other, it is necessary to find out the influencing factors of the mismatch between blood and blood. The relevant tests are conducted according to the operation rules and combined with the clinical history data to improve the accuracy of the cross-match blood test results.