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通过对81例重症胎粪吸入综合征 (MAS)机械通气的过程及参数分析 ,以了解机械通气对重症MAS的干预效果。对上海新华医院等9家医院的81例重度MAS ,用SAS软件对与疗效有关的因素进行秩和和χ2检验进行分析。81例中死亡32例 (39.5 % ) ,胎龄、1分钟Apgar评分、气胸及FiO2、PIP、MAP与疗效有关 ;48小时PH、72小时PaCO2、PaO2 及12小时后的SpO2 可判断预后。结果表明呼吸机治疗重症MAS死亡率仍较高 (接近40 % ) ,提示需重新认识常频通气对重症MAS的治疗效果。
81 cases of severe meconium aspiration syndrome (MAS) mechanical ventilation process and parameter analysis to understand the intervention effect of mechanical ventilation on severe MAS. Eighty-one patients with severe MAS in 9 hospitals including Shanghai Xinhua Hospital were analyzed by rank sum and χ2 test using SAS software. 32 cases died (39.5%), gestational age, 1 minute Apgar score, pneumothorax and FiO2, PIP, MAP were related to the curative effect; 48 hours PH, 72 hours PaCO2, PaO2 and 12 hours after the SpO2 can determine the prognosis. The results showed that ventilator treatment of severe MAS mortality is still high (close to 40%), suggesting the need to re-recognize the frequent treatment of severe MAS MAS treatment.