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目的分析探讨前列地尔治疗高龄糖尿病并慢性肾脏病患者的临床效果和安全性。方法 86例高龄糖尿病并慢性肾脏病患者,按照入院先后顺序分为对照组和实验组,每组43例。对照组接受常规治疗,实验组接受前列地尔治疗。比较两组患者各项指标和不良反应发生率。结果实验组患者各项指标变化明显优于对照组,不良反应发生率明显低于对照组,组间比较差异具有统计学意义(P<0.05)。结论在高龄糖尿病并慢性肾脏病患者治疗中应用前列地尔,其治疗效果显著,同时降低不良反应发生率,具有较高的临床应用价值。
Objective To investigate the clinical effect and safety of alprostadil in the treatment of elderly patients with diabetes and chronic kidney disease. Methods A total of 86 elderly patients with diabetic nephropathy and chronic kidney disease were divided into control group and experimental group according to the order of admission, with 43 cases in each group. Control group received routine treatment, experimental group received alprostadil treatment. The two groups of patients with indicators and the incidence of adverse reactions. Results All the indexes in the experimental group were significantly better than those in the control group, and the incidence of adverse reactions was significantly lower than that in the control group. The difference between the two groups was statistically significant (P <0.05). Conclusion The application of alprostadil in the treatment of elderly patients with chronic kidney disease and diabetes mellitus, its treatment effect is significant, while reducing the incidence of adverse reactions, with high clinical value.