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目的了解本地区近期支原体感染及药敏的情况,为临床正确用药提供参考资料;方法对347例非淋菌性泌尿生殖道炎患者进行支原体培养及药敏试验;结果(1)支原体培养阳性率为46.69%;(2)对解脲支原体(UU)单纯感染敏感率较高的有克拉霉素(CLA,97.4%)、强力霉素(DOX,91.3%),敏感率都在90%以上,对人型支原体(MH)单纯感染敏感率最高的是交沙霉素(JOS)和米诺环素(MIN,均为83.6),对UU+MH混合感染敏感率较高的有DOX(73.4%)、MIN(60.4%);结论四环素类和大环内酯类药物作为临床治疗非淋菌性尿道炎的一线用药,喹钠酮类可作为二线用药。
Objective To understand the recent cases of Mycoplasma infection and drug sensitivity in this area and to provide reference materials for clinical correct medication.Methods 347 cases of non-gonococcal genitourinary tract inflammation were tested for mycoplasma culture and drug sensitivity test.Results (1) The positive rate of mycoplasma culture was 46.69%; (2) clarithromycin (CLA, 97.4%) and doxorubicin (DOX, 91.3%) were sensitive to simple infection of UU, The most sensitive single infection of Mycoplasma hominis (MH) was josamycin (JOS) and minocycline (MIN, 83.6%). DOX (73.4% , MIN (60.4%). Conclusion Tetracyclines and macrolides are the first-line drugs for the clinical treatment of non-gonococcal urethritis. Quinones can be used as second-line drugs.