泡性角膜结膜炎多发于儿童。长期来认为是结核菌蛋白引起的迟发性超敏反应。近来认识到与其他细菌的蛋白也有关系。本病是对一些异性蛋白的非特异性迟发超敏反应。泡性角膜结膜炎常局部用皮质类固醇治疗,但长期应用并非经常有效,且可导致严重的眼部并发症。作者用口服四环素的方法成功的治疗6例病人,其中3例曾长期局部应用皮质类固醇和抗菌素治疗无效。 6例病人中泡性角膜结膜炎症状达3个月或3个月以上者5人;3人长达2年或更久。6例中3人局部曾用0.125%磷酸强的松龙每天1-4次,长达1-4年,仍复发3-8次。另外3人中2人接受抗菌素治疗,但病情无明显进步,也曾有 Vesicular keratoconjunctivitis in children. Long considered to be tuberculosis protein caused by delayed hypersensitivity. It has recently come to realize that proteins are also involved with other bacteria. The disease is a non-specific heterosexual delayed non-specific hypersensitivity. Follicular keratoconjunctivitis often treated with corticosteroids, but long-term use is not always effective, and can lead to serious eye complications. The authors successfully treated 6 patients with oral tetracycline, 3 of whom had long-term topical corticosteroid and antibiotic therapy failure. 6 patients with corneal keratoconjunctivitis symptoms for 3 months or more than 5 people; 3 people up to 2 years or longer. Of the 6 patients, 3 had had 0.125% prednisolone phosphate once daily for 1 to 4 years and 3 to 8 recurrences. Two of the other three were treated with antibiotics, but no significant improvement in the condition, there have been