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目的评价两种不同给药方法的成本-效果,以寻找一种高效经济的给药方案预防剖宫产术后感染,减少医药资源的浪费。方法采用随机病例对照试验,117例剖宫产手术患者被随机分为两组,实验组57例于术前30 min静脉给予单剂量头孢唑啉,术后6 h再追加一剂;对照组60例术后接受3 d q12h一次头孢唑啉的静脉给药。并评价术后预防感染的效果。结果试验组有效率96.5%,对照组有效率95.0%。试验组住院总费用为(4 929.19±87.44)元,对照组住院总费用为(5 767.03±99.01)元。试验组成本-效果比为51.08,对照组成本-效果比为60.71。结论试验组给药方案可有效预防剖宫产术感染,经济学效果更佳。
Objective To evaluate the cost-effectiveness of two different administration methods in order to find an efficient and economical dosing regimen to prevent post-cesarean infection and reduce the waste of medical resources. Methods A randomized controlled case-control study was conducted in 117 patients undergoing cesarean section. Fifty-seven patients in experimental group were given a single dose of cefazolin intravenously 30 min before operation and one additional dose 6 h after operation. Control group 60 Cases received three days after q12h cefazolin intravenous administration. And evaluate the effect of postoperative infection prevention. Results The experimental group was 96.5% efficient, control group 95.0% efficient. The total cost of hospitalization was (4 929.19 ± 87.44) yuan in the experimental group and (5 767.03 ± 99.01) yuan in the control group. The cost-effectiveness ratio of the experimental group was 51.08, and the cost-effectiveness ratio of the control group was 60.71. Conclusion The experimental group can effectively prevent cesarean section infection and improve the economics.