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心力衰竭(心衰)是各种心脏疾病发展至最后的临床综合征,心室重塑是心衰进展的重要机制。心肌细胞的丢失和室壁纤维化促进心室重塑。肌钙蛋白T是心肌细胞损伤的特异性标志物。大部分心衰患者血浆中可检测到肌钙蛋白T,提示心衰进展中持续存在慢性心肌损伤。研究表明心衰患者肌钙蛋白T浓度与心衰严重程度及发生不良事件的危险性密切相关,可较准确地提供患者预后信息。肌钙蛋白T可作为预后的一项重要生化标志物。现就肌钙蛋白T对心衰的预后研究做一综述。
Heart failure (heart failure) is the clinical syndrome with the development of various heart diseases. Ventricular remodeling is an important mechanism of heart failure progression. Cardiomyocyte loss and ventricular fibrosis promote ventricular remodeling. Troponin T is a specific marker of cardiomyocyte injury. Troponin T can be detected in the plasma of most patients with heart failure, suggesting that chronic myocardial damage persists in the progression of heart failure. Studies have shown that patients with heart failure Troponin T concentration and severity of heart failure and the risk of adverse events are closely related to the prognosis can provide more accurate information. Troponin T can be used as an important biochemical marker of prognosis. Now on the troponin T prognosis of heart failure to do a review.