论文部分内容阅读
为探索胸主动脉夹层发展与血液动力学因素的关系,借助计算流体动力学,对DeBakeyⅢ型胸主动脉夹层血液脉动流在正常血压和高血压下进行三维数值模拟,获得了夹层血液流动在一个心动周期内不同时刻真假腔纵向切面流线分布、真假腔入口横断面流线分布以及血管壁面压力和剪应力分布.计算结果表明,尽管血压值对血管壁面剪应力分布影响较小,但血压与真假腔内血液动力学行为密切相关;心缩期夹层假腔内压力远大于真腔内压力,夹层可能继续向下延伸发展.
To explore the relationship between the development of thoracic aortic dissection and hemodynamic factors, with the help of computational fluid dynamics, three-dimensional numerical simulation of blood flow of DeBakey Ⅲ thoracic aortic dissection under normotensive and hypertensive conditions was performed, The distribution of longitudinal streamline in the true and false cavities at different time points during the cardiac cycle, the streamline distribution at the entrance of the true and false lumen and the distribution of the pressure and shear stress on the vascular wall surface. The results show that although blood pressure has little effect on the distribution of shear stress on the vascular wall, Blood pressure is closely related to true and false intracavitary hemodynamic behavior; the pressure inside the false lumen of the systolic dissection is much larger than the pressure inside the true lumen, and the dissection may continue to extend downward.