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ERCC1是核苷酸切除修复(nucleotide excision repair,NER)途径的限速酶,在NER中起到限速或调节作用,ERCC1还是人体重要的DNA修复基因家族重要成员,
ERCC1 is the rate-limiting enzyme in nucleotide excision repair (NER) pathway, which plays a role in speed-limiting or regulation in NER. ERCC1 is also an important member of the human DNA repair gene family,