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在病毒性肝炎时,全血细胞减少伴不同程度骨髓增生低下较罕见,至今发表约有100例。存活数仍仅约10%。本文作者复习了文献中102例肝炎发作后9个月内发生全血细胞减少的病例,其中22例因各种影响因素而摒弃,仅从80例资料作了分析:肝炎发作平均年龄18岁,75%小于20岁;大约2/3是男性。75%病例在肝炎发作2月内发展为再生障碍性贫血,此时,肝功能和组织学一般显示亚急性或缓解阶段。虽用抗菌素、肾上腺皮质激素、血液制品、男性素等治疗,仍有87%病人死亡,平均存活11周,2/3病例于2月内
In viral hepatitis, pancytopenia with varying degrees of bone marrow hyperplasia is rare, about 100 cases have been published. The number of survivors is still only about 10%. The authors reviewed 102 cases of pancytopenia within the first 9 months after the onset of hepatitis in the literature, of which 22 were rejected for various influencing factors. Only 80 data were analyzed: the average age of hepatitis was 18 years, 75 % Is less than 20 years old; about 2/3 is male. Seventy-five percent of cases develop aplastic anemia within 2 months of the onset of hepatitis, when liver function and histology generally show subacute or remission stages. Although antibiotics, adrenal cortical hormones, blood products, such as male hormone treatment, there are still 87% of patients died, the average survival of 11 weeks, 2/3 cases in February