论文部分内容阅读
Lisinopril 是一种血管紧张素转换酶抑制剂,治疗原发性高血压与充血性心力衰竭均有效。其优点是一天服药一次作用可持续24小时,与心痛定和美托洛尔的对比研究证实,Lisinopril 疗效好,易耐受。阿替洛尔是一种心脏选择性β-阻滞剂,也是一天服一次。本研究是多中心、双盲、随机前瞻性用上述二种药物进行对比。144例原发性高血压患者,年龄≥18岁,坐位舒张期血压为12.7～17.3kPa,服安慰剂2周后给 Lisinopril 10～40mg/d 或阿替洛尔50～100mg/d,治疗8周后 Lisinopril 组(75例)坐位血压降低3.5/
Lisinopril is an angiotensin-converting enzyme inhibitor that is effective in treating essential hypertension and congestive heart failure. The advantage is that once a day medication for a sustainable 24-hour, and nifedipine and metoprolol comparative study confirmed that Lisinopril good effect, easy to tolerate. Atenolol is a cardioselective β-blocker that is also taken once a day. This study was multicenter, double-blind, randomized prospectively compared with the two drugs mentioned above. 144 patients with essential hypertension, age ≥ 18 years old, sitting diastolic blood pressure of 12.7 ~ 17.3kPa, 2 weeks after taking placebo Lisinopril 10 ~ 40mg / a or atenolol 50 ~ 100mg / d, treatment 8 Week Lisinopril group (75 cases) decreased blood pressure 3.5 /