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本文研究心衰时血清C反应蛋白(CRP)变化的规律及其对心衰的诊断价值。急性心衰组纠正心衰治疗前、后的CRP浓度分别为35.1±1.21与7.4±1.94μg/ml,有非常显著性差异(P<0.01);慢性心衰组治疗前、后的CRP浓度分别为4.2±0.92与3.2±1.71μg/ml,无显著差异(P>0.05)。而对照组治疗前、后CRP浓度均在正常范围(<3μg/ml)。急性心衰组CRP升高的程度与EF呈负相关。CRP升高者无1例有GPT升高。说明CRP升高的程度对急性左心衰竭的严重程度及治疗效果可能提供了一种有效、简单、且较敏感的检测指标。
This article studies the changes of serum C-reactive protein (CRP) during heart failure and its diagnostic value for heart failure. CRP concentrations in acute heart failure group before and after heart failure treatment were 35.1 ± 1.21 and 7.4 ± 1.94 μg / ml, respectively, with significant difference (P <0.01); CRP concentrations in chronic heart failure group before and after treatment were 4.2 ± 0.92 and 3.2 ± 1.71μg / ml, no significant difference (P> 0.05). The control group before and after treatment CRP concentrations were in the normal range (<3μg / ml). The level of CRP in acute heart failure group was negatively correlated with EF. None of the patients with elevated CRP had elevated GPT. Indicating that the degree of CRP increased the severity of acute left heart failure and treatment may provide an effective, simple and sensitive detection of indicators.