本文报告66例皮肤淀粉样变苔藓。本病易发病于中年,病程长,有剧烈瘙痒,皮损为扁平丘疹到圆锥形硬角化丘疹,好发于胫前,组织病理示真皮乳头有淡伊红染色均匀的淀粉样蛋白物质沉积,结晶紫染色有紫红色的异染性。表皮各层增厚伴有色素失禁等继发病变。淀扮样蛋白可能来源于变性的表皮细胞。 This article reports 66 cases of skin amyloidosis moss. The disease is susceptible to disease in middle age, long duration, severe itching, skin lesions for the flat papules to conical hard keratotic papules, occur in the anterior tibial, histopathological dermis nipple thin with light red staining of amyloid protein Deposition, Crystal violet staining with purple-red heterotic. Thickened layers of epidermis accompanied by secondary lesions such as pigment incontinence. Amyloid-like proteins may originate from degenerative epidermal cells.