论文部分内容阅读
目的研究静脉滴注丙种球蛋白治疗特发性血小板减少性紫癜(ITP)的临床疗效。方法将82例ITP患者随机分为两组治疗:对照组46例,予地塞米松0.2 mg/(kg.d),连用5 d,后改泼尼松每日1.5 mg/kg,分次口服,总疗程4～6周;治疗组36例,在对照组基础上予静脉滴注丙种球蛋白0.4 g/(kg.d),连用5 d。结果治疗组与对照组有效率差异无统计学意义,但治疗组止血时间、血小板计数达正常时间、血小板计数达峰值时间、以及血小板计数峰值均优于对照组,差异无统计学意义。结论静脉丙球联合地塞米松治疗ITP较单纯应用地塞来松能够更快地升高血小板,可作为首选治疗方法。
Objective To study the clinical efficacy of intravenous gamma globulin in the treatment of idiopathic thrombocytopenic purpura (ITP). Methods Eighty-two patients with ITP were randomly divided into two groups: control group (n = 46), dexamethasone 0.2 mg / (kg · d) for 5 days, and then prednisone 1.5 mg / kg , The total course of treatment of 4 to 6 weeks; 36 cases of treatment group, on the basis of the control group intravenous gamma globulin 0.4 g / (kg.d), once every 5 d. Results There was no significant difference in the effective rates between the treatment group and the control group. However, there was no significant difference between the treatment group and the control group in the hemostatic time, platelet count up to normal time, platelet count up to peak time, and platelet count peak. Conclusion Intravenous corticosteroids combined with dexamethasone treatment of ITP than simple application of dexamethasone can increase platelets faster, can be used as the preferred method of treatment.