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目的:评估同时切除前列腺和膀胱肿瘤对膀胱肿瘤在膀胱颈部和(或)前列腺窝处复发的影响。方法:回顾性研究47例同时行经尿道膀胱肿瘤电切术和经尿道前列腺切除术的患者,分为膀胱肿瘤单发组26例和多发组21例,记录随访时间、肿瘤的复发时间、复发位置、复发数量以及肿瘤的进展,综合评价同时切除前列腺及膀胱肿瘤和膀胱肿瘤复发的关系。结果:所有患者随访1～4年,平均随访2.9年;膀胱肿瘤的平均复发率为68.1%,单发组复发率为53.8%,多发组复发率为85.7%,两组复发率差异有统计学意义(P<0.05);肿瘤平均复发时间15.1个月,单发组复发时间17.5个月,多发组复发时间12.4个月;在膀胱颈和(或)前列腺窝肿瘤复发10例(21.3%);在前列腺窝膀胱肿瘤平均复发时间为21.3个月,在单发组为26.0个月,而在多发组为20.6个月。3例患者(6.3%)最后发展为浸润性膀胱癌而行膀胱全切术。结论:同时切除前列腺和膀胱肿瘤是一种比较安全的手术策略,对膀胱肿瘤在膀胱颈和前列腺窝处的复发没有影响。
PURPOSE: To assess the effect of simultaneous resection of prostate and bladder tumors on the recurrence of bladder tumors in the bladder neck and / or prostate. Methods: A total of 47 patients undergoing transurethral resection of the bladder tumor and transurethral resection of the prostate were retrospectively studied. Twenty-six patients with bladder cancer and 21 patients with multiple tumors were retrospectively studied. The follow-up time, recurrence time, , The number of recurrence and the progress of the tumor, a comprehensive evaluation of the resection of prostate and bladder cancer and bladder tumor recurrence relationship. Results: All patients were followed up for 1 to 4 years, with an average follow-up of 2.9 years. The average recurrence rate of bladder cancer was 68.1%. The recurrence rate was 53.8% in single group and 85.7% in multiple group. The difference was statistically significant (P <0.05). The mean tumor recurrence time was 15.1 months, the recurrence time was 17.5 months in single group and the recurrence time was 12.4 months in multiple group, and 10 cases (21.3%) in bladder neck and / or prostate tumor. The mean recurrence time was 21.3 months in prostate fossa tumors, 26.0 months in the single-case group and 20.6 months in the multiple-arm group. Three patients (6.3%) eventually developed invasive bladder cancer while undergoing total bladder surgery. Conclusions: Simultaneous resection of prostate and bladder tumors is a safer surgical strategy that has no effect on the recurrence of bladder tumors in the bladder neck and prostate fossa.