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目的:探讨间质性肺疾病(ILD)的临床诊断、鉴别诊断及对预后判断的意义。方法:对45例以弥漫性肺间质病变为主要表现患者的临床症状、体征、X线胸片和高分辨率CT表现及其他辅助检查等结果进行回顾性分析。结果:在此45例患者中,确诊为特发性肺纤维化(IPF)的29例,结缔组织致肺间质纤维化(PIF)的8例,粉尘所致肺纤维化的6例,药物引起的3例;COPD合并PIF的19例,PIF合并慢性肺源性心脏病的22例,PIF合并感染的40例。结论:ILD的治疗方案的选择主要取决于IDL的病因诊断以及病人的整体健康状况。
Objective: To investigate the clinical diagnosis, differential diagnosis and prognostic significance of interstitial lung disease (ILD). Methods: 45 patients with diffuse pulmonary interstitial disease as the main manifestation of clinical symptoms, signs, chest X-ray and high resolution CT findings and other auxiliary examination results were retrospectively analyzed. RESULTS: Of the 45 patients, 29 were diagnosed with idiopathic pulmonary fibrosis (IPF), 8 with connective tissue-induced pulmonary fibrosis (PIF), 6 with dust-induced pulmonary fibrosis, Caused by 3 cases; COPD with PIF in 19 cases, PIF with 22 cases of chronic cor pulmonale, PIF with infection in 40 cases. CONCLUSIONS: The choice of treatment regimen for ILD depends primarily on the etiological diagnosis of IDL and on the general health of the patient.