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目的 探讨2型糖尿病肾病气阴两虚证与彩色多普勒部分客观化指标的相关性,为其客观化研究提供新的理论.方法 选择2型糖尿病肾病中气阴两虚证患者209例,正常对照组50例.首先采用二维图像观察DN肾脏的大小及实质回声;再用CDFI观察肾血流灌注程度;再用脉冲波多普勒观察主肾动脉、段间动脉及叶间动脉血流频谱,测量收缩期峰值血流速度(VS)、舒张期末血流速度(VD)、平均血流速度(VM)、搏动指数(PI)、阻力指数(RI)值.结果 (1)气阴两虚患者肾脏体积基本正常,与正常组比较,差异不显著(P>0.05).(2)彩色多普勒观察到的肾实质回声与气阴两虚证存在一定的相关性,R气阴两虚=0.4046±0.0404,且气阴两虚证与正常对照组对比,一致性中度.(3)肾动脉血流的灌注程度与气阴两虚证存在的相关性,R气阴两虚=0.4146±0.0399.(4)MRA、SRA、IRA的血流频谱指标VS、VD、VM、PI、RI与气阴两虚证存在相关性;气阴两虚证与正常对照组比较,差异显著或非常显著(P<0.05,P0.05).(2)There is a certain correlation between renal parenchyma echo observed with color Doppler and qi and yin deficiency syndrome, R qi and yin dificeny =0.4046 + 0.0404, and there is a moderate consistency with Qi Yin deficiency syndrome and grade II contrast;(3) there is a certain correlation between the degree of perfusion of renal artery blood flow and qi and yin deficiency syndrome, R qi and yin dificeny =0.4146 + 0.0399.(4) There is a certain correlation bteween blood flow spectrum indexes VS, VD, VM, PI, RI of MRA, SRA, IRA of and qi and yin deficiency syndrome, compared with normal control group, the difference was significant or very significant (P<0.05, P<0.01).Conclusion There is a certain correlation between type 2 diabetic nephropathy with Qi and yin deficiency syndrome and the size of renal parenchyma echo, the degree of blood perfusion and the hemodynamics of renal artery branches.