胎粪吸入综合征(meconium aspiration syndrome,MAS)是指患儿在宫内或产时吸入胎粪污染的羊水后引起的一系列由各种炎症介质介导的炎症性疾病,可累全身各个器官及系统,临床症状因吸入胎粪量及羊水污染程度不同而表现不同。国外研究[1-2]显示,有7%~22%的足月新生儿羊水被胎粪污染,其中仅有1%会发生MAS。我国既往调查结果显示,MAS在成活新生儿中发病率为1.2%~2.2%[3]。 Meconium aspiration syndrome (MAS) refers to a series of inflammatory diseases mediated by various inflammatory mediators caused by intrauterine or intrapartum or intrapartum or intrapartum inhalation of amniotic fluid contaminated amniotic fluid, which can affect various organs of the whole body And the system, clinical symptoms due to different levels of amniotic fluid intake and amniotic fluid contamination and performance. Foreign studies [1-2] showed that 7% to 22% of full-term neonatal amniotic fluid contamination by meconium, of which only 1% of the occurrence of MAS. Our previous survey results show that the incidence of MAS in the survival of newborns was 1.2% to 2.2% [3].