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目的巩固基本消除丝虫病的成果,了解基本消除丝虫病后的流行动态和传播规律,为消灭丝虫病提供科学依据。方法在65个原丝虫病流行县开展病原学、蚊媒、血清学纵向和横向监测。结果65个县(市)连续13～23年的横向监测显示,已连续7～23年未发现微丝蚴阳性者,蚊媒监测9-23年无人体幼丝虫感染。65个县(市)中有41个县(市)基本消除丝虫病后10年内的监测乡和人口覆盖率分别为43.65%和5.08%,10年后再监测的监测乡和人口覆盖率分别为15.96%和1.25%;24个县(市)基本消除后10年以上病原学监测乡和人口覆盖率分别为39.14%和3.94%。11个纵向监测点观察13～20年,发现的14例残存微丝蚴血症者,在未采取治疗措施的情况下,均于次年转阴。血清学(IFAT)监测人群抗体水平已和非流行区人群相近。结论浙江省丝虫病传播已被阻断,已实现全省消除丝虫病。
Objective To consolidate the basic elimination of filariasis results, to understand the basic elimination of filariasis after the epidemic dynamics and propagation, in order to provide a scientific basis for the elimination of filariasis. Methods Etiological, mosquito-borne, serological longitudinal and lateral surveillance were performed in 65 endemic filar endemic counties. Results The lateral monitoring of 65 counties (cities) for 13 to 23 consecutive years showed that no microfilariae was found in 7 ~ 23 consecutive years and no mosquito infection was detected by mosquito media in 9-23 years. In 41 counties (cities) of 65 counties, the monitoring townships and population coverage within 10 years after basic elimination of filariasis were 43.65% and 5.08% respectively. The monitoring townships and population coverage rates monitored again after 10 years 15.96% and 1.25% respectively. The etiological monitoring township and population coverage of over 10 years in 24 counties (cities) were 39.14% and 3.94% respectively. 11 longitudinal monitoring points observed 13 to 20 years, found in 14 cases of residual microfilaremia who did not take treatment measures, were negative in the following year. Antibody levels in serological (IFAT) surveillance populations have been similar to those in non-endemic areas. Conclusion The transmission of filariasis in Zhejiang Province has been blocked, and the province has eliminated filariasis.