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目的观察在常规治疗的基础上加酪酸梭菌活菌片治疗新生儿高胆红素血症的疗效。方法将90例新生儿高胆红素血症患儿随机分成治疗组和对照组,每组45例。两组患儿均应用常规治疗,治疗组在此基础上加用酪酸梭菌活菌片口服,并观察两组患儿日均胆红素水平及黄疸消退时间的变化。结果治疗组日均胆红素下降水平明显高于对照组,黄疸消退时间明显短于对照组(P<0.05)。结论在常规治疗的基础上加用酪酸梭菌活菌片治疗新生儿高胆红素血症,可迅速降低胆红素水平,缩短治疗时间。
Objective To observe the curative effect of live Clostridium butyricum on neonatal hyperbilirubinemia on the basis of routine treatment. Methods 90 cases of neonatal hyperbilirubinemia were randomly divided into treatment group and control group, 45 cases in each group. The two groups of children were treated with conventional treatment, the treatment group on the basis of the addition of live Clostridium butyricum oral tablets, and observed the average daily bilirubin levels in children and jaundice subsided time changes. Results The daily average level of bilirubin in the treatment group was significantly lower than that in the control group, and the regression time of jaundice was significantly shorter than that of the control group (P <0.05). Conclusion Adding Clostridium butyricum viable bacterium tablets to neonatal hyperbilirubinemia based on routine treatment can rapidly reduce the level of bilirubin and shorten the treatment time.